Table 2 Single-mode aptamer biosensors based on nanozymes for cancer cell-derived exosomes detection
From: Nanozyme-based aptasensors for the detection of tumor biomarkers
Cell Line | Aptamer | Nanozyme | Substrate | Detection Method | Linear Range | LOD | Recovery (RSD) | Assay Time | Ref. |
|---|---|---|---|---|---|---|---|---|---|
MGC-803 | MUC-1 EpCAM HER2 | C3N4 nanosheet | oPD/H2O2 | Fluorescence | 8.53 × 103−3.01 × 106 particles/mL | 2.5 × 103 particles/mL | − | − | [63] |
HGC-7910 | CD63 | MoS2 -MIL-101(Fe) | TMB/H2O2 | Colorimetry | 1.6 × 104−1.6 × 106 particles/µL | 3.37 × 103 particles/µL | 95 − 103% | − | [36] |
MCF-7 | CD63 | Fe3O4-Cu2+ | TMB/H2O2 | Colorimetry | 1.4 × 104−5.6 × 105 particles/µL | 5.91 × 103 particles/µL | − | − | [37] |